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CISDOC database

Document ID (ISN)30058
CIS number 78-1637
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1978
Convention or series no.
Author(s) Sugimoto K., Goto S., Kanda S., Taniguchi H., Nakamura K., Baba T.
Title Studies on angiopathy due to carbon disulfide - Retinopathy and index of exposure dosages.
Bibliographic information June 1978, Vol.4, No.2, p.151-158. Illus. 14 ref.
Abstract Retinopathy (microaneurisms, small dot haemorrhages) and the coded resting and postexercise findings suggestive of coronary heart disease (CHD) were studied in 420 male workers exposed to carbon disulfide (CS2) and 390 non-exposed. Retinopathy was detected in 24.4% of the exposed and 3.8% of the non-exposed workers by colour fundus photography. Among exposed workers, there was a significant correlation between retinopathy and index of exposure dosages (a value calculated from worker history and time-weighted average CS2 concentrations). The relation between retinopathy and exposure duration was not so high. The occurrences of coded resting and postexercise "coronary" ECG findings were not related to the index of exposure dosages. Risk factors for CHD such as total serum cholesterol, triglycerides, beta-lipoproteins, blood pressure, obesity and skinfold thickness were simultaneously studied. These variables were not important in the development of angiopathy due to CS2, especially the so-called retinopathia sulfocarbonica.
Descriptors (primary) diseases of retina and optic nerve; carbon disulfide; viscose rayon industry; coronary diseases
Descriptors (secondary) eye examinations; comparative study; exposure evaluation
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Inorganic substances
Diseases of the eye and vision damage
Cardiovascular diseases
Inorganic sulfur compounds