Document ID (ISN) | 30010 |
CIS number |
78-1624 |
ISSN - Serial title |
0301-1518 - Nouvelle presse médicale |
Year |
1978 |
Convention or series no. |
|
Author(s) |
Yver L., Maréchaud R., Picaud D., Touchard G., Talin d'Eyzac A., Matuchansky C., Patte D. |
Title |
Acute renal insufficiency during lead poisoning - Responsibility of the chelating agent |
Original title |
Insuffisance rénale aiguë au cours d'un saturnisme professionel - Responsabilité du traitement chélateur. [in French] |
Bibliographic information |
6 May 1978, Vol.7, No.18, p.1541-1543. 13 ref. |
Abstract |
Report on a case of acute renal insufficiency occurring after administration of 1g EDTA daily for occupational lead poisoning in a printing worker, which caused massive elimination of lead (15,000µg/24h). The study provides new evidence concerning the mechanism of kidney toxicity of the chelating agent and aids clarification of the cause of renal lesions due to lead. The best prevention of renal complications of treatment by chelating agents appears to be surveillance of urinary lead levels, which should remain at 1,000-2,000µg/24h, a level which is not toxic for the kidney. |
Descriptors (primary) |
lead; EDTA; chelation therapy; chronic poisoning; renal insufficiency |
Descriptors (secondary) |
printing industry; acute forms; urine monitoring; nephrotoxic effects; case study |
Document type |
E - Books, reports, proceedings |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Inorganic substances Diseases of the kidney and the urinary system Lead and compounds
|