| Document ID (ISN) | 29262 |
| CIS number |
78-764 |
| ISSN - Serial title |
0003-9896 - Archives of Environmental Health |
| Year |
1977 |
| Convention or series no. |
|
| Author(s) |
Lilis R., Fischbein A., Diamond S., Anderson H.A., Selikoff I.J., Blumberg W.E., Eisinger J. |
| Title |
Lead effects among secondary lead smelter workers with blood lead levels below 80µg/100ml. |
| Bibliographic information |
Nov.-Dec. 1977, Vol.32, No.6, p.256-266. Illus. 31 ref. |
| Abstract |
Groups of 158 foundry workers and 24 workers from other plants in the same area were studied; 71% of the foundry workers had less than 80µg/100ml lead in blood and no history of elevated concentrations. In the 71% subgroup, central nervous system symptoms (tiredness, sleeplessness, irritability, headache) were reported by 55% of the group and muscle and joint pain by 39%. Zinc protoporphyrin (ZPP) levels were elevated in 71% of cases. Low haemoglobin levels (less than 14g/100ml) were found in more than a third of the workers. While blood urea nitrogen (BUN) and creatinine were mostly in the normal range, there was a correlation between ZPP and both BUN and creatinine. Reduced nerve-conduction velocities were present in 25% of the group; this was not significantly different from findings in a control group. A blood level of 80µg/100ml is an inappropriate biological guide in the prevention of lead disease. |
| Descriptors (primary) |
lead; foundries; biological effects |
| Descriptors (secondary) |
protoporphyrin; USA; central nervous system; creatinine; biological threshold limits; occupational health survey; conduction velocity; serum zinc level; symptoms |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Foundries, metalcasting and forging operations
Lead and compounds
|
