| Document ID (ISN) | 28403 |
| CIS number |
78-163 |
| Year |
1977 |
| Convention or series no. |
|
| Author(s) |
Steward R.D., Hake C.L., Wu Z., Kalbfleisch J., Newton P.E., Marlow S.K., Vucicevic-Salama M. |
| Title |
Effects of perchloroethylene/drug interaction on behaviour and neurological function. |
| Bibliographic information |
DHEW Publication No.(NIOSH)77-191, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA, Apr. 1977. 145p. Illus. 23 ref. |
| Abstract |
This study attempted to determine the degree of hazard if the effect of a central nervous system depressant is added to the effect of perchloroethylene (PCE) exposure. There appeared to be no decreases in neurological or behavioural performance due to the combined effects of the substances. Six men and six women volunteers were exposed to PCE vapour and ethanol (as vodka) or diazepam was added. Several neurological and behavioural tests were given at peak blood levels of the drugs. There were decreases in performances with the drugs alone. |
| Descriptors (primary) |
tetrachloroethylene; ethanol; neuropsychic effects; neurological effects; drugs |
| Descriptors (secondary) |
USA; report; diazepam; synergism; human experiments; behaviour study; degreasing agents |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Alcohols
Diseases of the nervous system
Halogenated hydrocarbons
|
