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CISDOC database

Document ID (ISN)28107
CIS number 77-1964
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1977
Convention or series no.
Author(s) Hahon N., Booth J.A., Eckert H.L.
Title Antagonistic activity of poly(4-vinylpyridine-N-oxide) to the inhibition of viral interferon induction by asbestos fibres.
Bibliographic information May 1977, Vol.34, No.2, p.119-125. 31 ref.
Abstract The depressive effect of various asbestos fibres on interferon induction by influenza virus was significantly diminished or abolished by pretreating either the asbestos fibres or cell monolayers with poly(4-vinylpyridine-N-oxide). Maximum antagonistic activity was time- and concentration-dependent. Pretreating asbestos fibres with the polymer was more rapid and effective than pretreating cell monolayers.
Descriptors (primary) antagonistic effects; viruses; asbestos; poly-4-vinylpyridine N-oxide
Descriptors (secondary) influenza; in vitro experiments; protective pharmacological agents
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Asbestos
Bacterial and parasitic diseases
Viral diseases (other than aids)
Influenza