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Document ID (ISN)27697
CIS number 77-1395
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1976
Convention or series no.
Author(s) Makulova M.D., Filičeva A.P.
Title Health status of triphthazine production workers
Original title Sostojanie zdorov'ja lic, zanjatyh v proizvodstve triftazina [in Russian]
Bibliographic information July 1976, No.7, p.27-30.
Abstract Results of observations and medical examinations of 57 pharmaceutical industry workers exposed to triphthazine (piperazine derivative of phenothiazine) dust for 2-5 years. The authors observed cases of acute poisoning characterised by general asthenia, increase of muscular tonicity and convulsions, and cases of subacute poisoning with similar but less severe symptoms (1 case study). In suspected chronic poisoning (headaches, autonomic disorders), medical supervision should be stepped up and therapeutic measures taken. Personnel showing acute or subacute poisoning should be given treatment and transferred to work not involving exposure.
Descriptors (primary) neurotoxic effects; pharmaceutical industry; functional nervous disorders; triphthazine
Descriptors (secondary) poisoning; USSR; case study; migraine; medical supervision; neurovegetative disorders; survey; transfer to other work; neurasthenia
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Pharmaceutical industry
Diseases of the nervous system
Mental health
Heterocyclic compounds