ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)27434
CIS number 77-1079
ISSN - Serial title 0003-9896 - Archives of Environmental Health
Year 1977
Convention or series no.
Author(s) Kimbrough R.D., Carter C.D., Liddle J.A., Cline R.E., Phillips P.E.
Title Epidemiology and pathology of a tetrachlorodibenzodioxin poisoning episode.
Bibliographic information Mar.-Apr. 1977, Vol.32, No.2, p.77-86. Illus. 31 ref.
Abstract An epidemiological and laboratory investigation of a poisoning outbreak that involved 3 riding arenas and killed 57 horses, 5 colts, and numerous other animals is described. The outbreak was traced to the spraying of the arenas with salvage oil contaminated with tetrachlorodibenzodioxin, trichlorophenol, and polychlorinated biphenyls. The contamination of the salvage oil resulted from the improper disposal of toxic industrial waste. In the tissues of the horses available for study, the most prominent lesion was a centrilobular fibrosis of the liver that arose in the wall of the central veins. This lesion resembled the chronic form of veno-occlusive disease of the liver in humans.
Descriptors (primary) poisoning; animals; tetrachlorodibenzodioxin
Descriptors (secondary) disposal of harmful waste; hepatotoxic effects; polychlorinated biphenyls; trichlorophenol; epidemiologic study; histopathology; used oils
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Animal hazards
Heterocyclic compounds