| Document ID (ISN) | 27008 |
| CIS number |
77-735 |
| ISSN - Serial title |
0098-7484 - Journal of the American Medical Association |
| Year |
1976 |
| Convention or series no. |
|
| Author(s) |
Folland D.S., Schaffner W., Ginn H.E., Crofford O.B., McMurray D.R. |
| Title |
Carbon tetrachloride toxicity potentiated by isopropyl alcohol. |
| Bibliographic information |
Oct. 1976, Vol.236, No.16, p.1853-1856. Illus. 20 ref. |
| Abstract |
Potentiation of carbon tetrachloride (CCl4) by isopropyl alcohol has previously been shown only in rats. Here 14 cases of toxicity in an isopropyl alcohol packaging plant following exposure to CCl4 are described. Renal failure or hepatitis developed in 4. Expired alveolar gas had high acetone levels and the workers were thus metabolically predisposed to CCl4 injury. Stricter limits for CCl4 exposure (present U.S. TLV: 10ppm) are required when there is concomitant exposure to isopropyl alcohol. |
| Descriptors (primary) |
carbon tetrachloride; synergism; toxicology; isopropyl alcohol |
| Descriptors (secondary) |
case study; renal dysfunction; isobutyl alcohol; bottling; long-term exposure; hepatitis |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Halogenated hydrocarbons
Alcohols
|
