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Document ID (ISN)26414
CIS number 77-144
ISSN - Serial title 0022-443X - Journal of Science of Labour - Rōdō Kagaku
Year 1976
Convention or series no.
Author(s) Osanai H.
Title An experimental study on hepatoma caused by aromatic amines.
Bibliographic information Apr. 1976, Vol.52, No.4, p.179-201. Illus. 49 ref.
Abstract In this long-term experimental study, 0,1% aromatic amines (3,3'-dihydroxybenzidine, dianisidine, 3,3'-dichlorobenzidine, 1-naphthylamine, 2-naphthylamine and 3,4,4'-triaminodiphenyl ether) were mixed in the food and given to mice, to determine the carcinogenic action on uptake by a natural route. Body and organ weights, blood values and hepatoma incidence are tabulated for the different amines and durations of administration. A high incidence of hepatoma resulted with all these aromatic amines. The tables, captions of the ilustrations and abstract are in English.
Descriptors (primary) carcinogens; liver cancer; aromatic amines
Descriptors (secondary) 1-naphthylamine; 4-(4-aminophenoxy)-o-phenylenediamine; dimethoxybenzidine; 3,3'-dihydroxybenzidine; benzidine; 3,3'-dichlorobenzidine; animal experiments; long-term study; 2-naphthylamine
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Aromatic amines