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CISDOC database
Document ID (ISN) | 26414 |
CIS number |
77-144 |
ISSN - Serial title |
0022-443X - Journal of Science of Labour - Rōdō Kagaku |
Year |
1976 |
Convention or series no. |
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Author(s) |
Osanai H. |
Title |
An experimental study on hepatoma caused by aromatic amines. |
Bibliographic information |
Apr. 1976, Vol.52, No.4, p.179-201. Illus. 49 ref. |
Abstract |
In this long-term experimental study, 0,1% aromatic amines (3,3'-dihydroxybenzidine, dianisidine, 3,3'-dichlorobenzidine, 1-naphthylamine, 2-naphthylamine and 3,4,4'-triaminodiphenyl ether) were mixed in the food and given to mice, to determine the carcinogenic action on uptake by a natural route. Body and organ weights, blood values and hepatoma incidence are tabulated for the different amines and durations of administration. A high incidence of hepatoma resulted with all these aromatic amines. The tables, captions of the ilustrations and abstract are in English. |
Descriptors (primary) |
carcinogens; liver cancer; aromatic amines |
Descriptors (secondary) |
1-naphthylamine; 4-(4-aminophenoxy)-o-phenylenediamine; dimethoxybenzidine; 3,3'-dihydroxybenzidine; benzidine; 3,3'-dichlorobenzidine; animal experiments; long-term study; 2-naphthylamine |
Document type |
- |
Subject(s) |
Toxic and dangerous substances
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Broad subject area(s) |
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Browse category(ies) |
Aromatic amines
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