| Document ID (ISN) | 26077 |
| CIS number |
76-1912 |
| Year |
1976 |
| Convention or series no. |
|
| Author(s) |
Åstrand I., Övrum P., Lindqvist T., Hultengren M. |
| Title |
Exposure to butanol - Uptake and distribution in man. |
| Original title |
Exposition för butanol - Upptag och distribution hos människa [in Swedish] |
| Bibliographic information |
Arbete och hälsa - Vetenskaplig skriftserie 1976:12, Arbetarskyddsverket, Stockholm, Sweden, 1976. 28p. Illus. 11 ref. |
| Abstract |
12 subjects were exposed for 2h to 200 or 600mg/m3 butanol in inspired air during rest and exercise on a bicycle ergometer. The butanol concentrations in arterial blood and in the last ("alveolar") part of expired air were low. The ratio of the "alveolar" concentration to inspired concentration was low in relation to the low percentage uptake. The solubility of butanol in water may explain the results; the alcohol was probably dissolved in the water of the mucuous membranes in the dead-space during inspiration. It was then partly released from the membranes and the concentration in the last part of the expiration was not the same as the concentration in the actual alveolar air. |
| Descriptors (primary) |
butanols; body retention; exposure evaluation |
| Descriptors (secondary) |
butyl alcohol; inhalation; determination in exhaled air; human experiments; determination in blood; exercise tests |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Exposure evaluation
Alcohols
|
