| Document ID (ISN) | 25372 |
| CIS number |
76-1073 |
| Year |
1975 |
| Convention or series no. |
|
| Author(s) |
Petersen R.V., Lyman D.J., Roll D.B., Swinyard E.A. |
| Title |
Toxicology of plastic devices having contact with blood. |
| Bibliographic information |
PB-244 753/OWV, National Technical Information Service, Springfield, Virginia 22151, USA, 1 May 1975. 122p. 67 ref. Price: Photocopy US-$5.25/Microfiche US-$2.25. |
| Abstract |
A collection of papers on the following subjects: acute LD50 of mono-2-ethylhexyl phthalate (MEHP) in mice and rats; sub-acute and local toxicity of MEHP in mice; in vitro uptake of bis(2-ethylhexyl)phthalate (DEHP) by rat heart tissues; DEHP effect on rat heart Na+, K+-ATPase; in vitro metabolism of DEHP by enzyme systems and analyses of organs of calves and humans exposed to cardiac by-pass and renal dialysis procedures; analyses of blood and organs of calves maintained on cardiac by-pass for extended periods of time; localisation of tritiated DEHP in the mouse; fate and metabolism of DEHP in Peromyscus Maniculatus; ultrastructural observations on lung tissue following DEHP administration; effects of DEHP on: hexobarbital sleep time, coagulation time in mice after administration of dicumarol, and reproduction in mice at low dosage; effect of a phthalate plasticiser on blood compatability of polyvinyl chloride; tissue culture studies on MEHP; etc. |
| Descriptors (primary) |
blood; metabolic process; plasticizers; phthalates; toxicology; polyvinyl chloride |
| Descriptors (secondary) |
particle size distribution; leukocytes; bis(ethylhexyl) phthalate; enzyme disturbances; mono(2-ethylhexyl) phthalate; in vitro experiments; chromosome changes; histopathology; metabolic studies; animal experiments |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Esters and salts
Genetic factors in reaction to exposures
Toxicology
Phthalates
|
