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CISDOC database
| Document ID (ISN) | 23853 |
| CIS number |
75-1750 |
| ISSN - Serial title |
0013-9351 - Environmental Research |
| Year |
1975 |
| Convention or series no. |
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| Author(s) |
Hoover R., Fraumeni J.F. |
| Title |
Cancer mortality in U.S. counties with chemical industries. |
| Bibliographic information |
Apr. 1975, Vol.9, No.2, p.196-207. Illus. 14 ref. |
| Abstract |
Geographic analysis of U.S. cancer mortality, 1950-1969, revealed excess rates for bladder, lung, liver, and other cancers among males in 139 counties where the chemical industry is highly concentrated. The correlation could not be explained by confounding variables such as urbanization, social economic class, or employment in non-chemical industries. If the excess cancer mortality in these areas is due to industrial exposures, the actual risk of cancer among certain chemical workers must be very high. The correlation was limited to counties associated with specific categories of the chemical industry. Bladder cancer showed strong positive gradients associated with dyes, intermediates, and organic pigments; drugs; perfumes and cosmetics. Lung cancer was associated with industrial gases, drugs, soaps and detergents, paints, inorganic pigments, and synthetic rubber. Liver cancer was associated with other organic chemicals, synthetic rubber, soaps and detergents, cosmetics, printing ink. Excess mortality appeared about ages 35-39, 45-49, and 50-54, respectively, for the three types. |
| Descriptors (primary) |
carcinogens; chemical industry; liver cancer; bladder tumour; lung cancer; USA |
| Descriptors (secondary) |
paint and varnish industry; cosmetics; perfumes; mortality; printing inks; detergent industry; geographical variables; synthetic rubber industry; dyestuff industry; pharmaceutical industry; age-linked differences |
| Document type |
- |
| Subject(s) |
Chemicals, plastics and rubber
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| Broad subject area(s) |
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| Browse category(ies) |
Chemical industry
Diseases of the respiratory system (except for pneumoconiosis & similar)
Diseases of the kidney and the urinary system
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