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CISDOC database

Document ID (ISN)22525
CIS number 75-482
ISSN - Serial title 0140-6736 - Lancet
Year 1974
Convention or series no.
Title Occupational leucoderma.
Bibliographic information Oct. 1974, Vol.2, No.7885, p.879. 9 ref.
Abstract A number of phenol and catechol compounds widely used in industry can produce cutaneous depigmentation when applied topically to the skin. Outbreaks of leucoderma have occurred in workers exposed to para-tertiary butylphenol and butylcatechol and in hospital workers exposed to phenols in germicidal disinfectants. Chemical workers engaged in the production of alkyl phenols are also at risk. Further research is needed to clarify the mechanism by which these compounds can induce cutaneous depigmentation.
Descriptors (primary) pigmentation disorders; benzene diols; phenols; leukoderma
Descriptors (secondary) chemical industry; p-tert-butylphenol; antioxidants; 4-tert-butylpyrocatechol; hospitals; disinfectants
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Skin diseases
Phenols and phenolic compounds