Document ID (ISN) | 21796 |
CIS number |
74-1695 |
ISSN - Serial title |
0007-1072 - British Journal of Industrial Medicine |
Year |
1974 |
Convention or series no. |
|
Author(s) |
Cramér K., Goyer R.A., Jagenburg R., Wilson M.H. |
Title |
Renal ultrastructure, renal function, and parameters of lead toxicity in workers with different periods of lead exposure. |
Bibliographic information |
Apr. 1974, Vol.31, No.2, p.113-127. Illus. 30 ref. |
Abstract |
Renal biopsies from 5 men with heavy occupational exposure to lead were compared with studies of their renal function and parameters of lead toxicity. 2 men had lead exposure of less than 1 year, while 3 had been exposed for from 4 to more than 30 years. Renal function studies were performed in 2 men from whom renal biopsies could not be obtained. The study demonstrates that the pathogenesis of chronic lead nephropathy is a continuum of morphological and functional change that can be divided into 2 stages which are described. |
Descriptors (primary) |
lead; nephrotoxic effects; renal damage |
Descriptors (secondary) |
enzyme inhibition; case study; ALAD; alcoholism; renal function tests; long-term exposure; histopathology; biopsy; urinary excretion |
Document type |
- |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Inorganic substances Alcohol and drug abuse Diseases of the kidney and the urinary system Lead and compounds
|