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CISDOC database

Document ID (ISN)21790
CIS number 74-1694
Year 1974
Convention or series no.
Author(s) Le Bourdon A.
Title Occupational depigmentations - A clinical case
Original title Les dépigmentations professionnelles (à propos d'un cas clinique). [in French]
Bibliographic information Université de Paris VI, Faculté de médecine Broussais - Hôtel-Dieu, Paris, France, 1974. 33p. Illus. 43 ref.
Abstract MD thesis. Description of a case of leukoderma of the hand involving a black worker using a hydroquinone developer. Review of the chemical substances responsible (hydroquinone, p-tolyl hydroquinone, p-tert-butylphenol, p-tert-butylpyrocatechol, 4-chloro-2-phenoxyphenol, propoxyphenol) and cases previously described in the medical literature. Problems of diagnosis, physiopathological hypotheses, biochemical mechanisms and stages of melanogenesis, treatment and prevention. The profound psychological effects of these types of leukoderma are emphasised, especially among black subjects on account of their resemblance to achromic leprosy.
Descriptors (primary) leukoderma; benzene diols; aromatic alcohols; phenols
Descriptors (secondary) literature survey; compensation of occupational diseases; p-tert-butylphenol; case study; France; hydroquinone monobenzyl ether; pathogenesis; diagnosis; thesis; 4-tert-butylpyrocatechol; medical prevention; medical treatment; hydroquinone; pigmentation disorders
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Skin diseases
Phenols and phenolic compounds