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CISDOC database

Document ID (ISN)21693
CIS number 74-1673
ISSN - Serial title 0003-9896 - Archives of Environmental Health
Year 1974
Convention or series no.
Author(s) Mahaffey K.R., Goyer R.A., Wilson M.H.
Title Influence of ethanol ingestion on lead toxicity in rats fed isocaloric diets.
Bibliographic information Apr. 1974, Vol.28, No.4, p.217-222. Illus. 27 ref.
Abstract An experiment was carried out to study the effect of ethanol ingestion on susceptibility to lead under conditions of controlled nutrient intake. The synergistic effect of alcohol on lead toxicity is slight when compared to the influence of previously studied nutritional factors such as calcium and iron. The study suggests that the clinically-suspected synergism between alcohol consumption and lead poisoning, sometimes observed among industrial workers, is more likely due to nutritional factors than to mutual enhancement of their closely-related cellular effects.
Descriptors (primary) lead; synergism; toxicology; ethanol
Descriptors (secondary) hepatic damage; histopathology; animal experiments
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Inorganic substances
Lead and compounds