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CISDOC database

Document ID (ISN)20141
CIS number 74-141
ISSN - Serial title 0091-6765 - Environmental Health Perspectives
Year 1973
Convention or series no.
Author(s) Autian J.
Title Toxicity and health threats of phthalate esters: Review of the literature.
Bibliographic information Experimental Issue No.4, June 1973, p.3-26. Illus. 56 ref.
Abstract Comprehensive review of recent literature on the subject and presentation of the results of animal experiments. Physical, chemical and toxic properties of a variety of phthalate esters are tabulated. Sections of the review are devoted to: chemistry, properties and applications; toxicology (acute, subacute and chronic toxicity; absorption, distribution, excretion and metabolism; teratogenic mutagenic and carcinogenic effects; cellular toxicity); environmental and ecological aspects.
Descriptors (primary) toxicology; phthalates
Descriptors (secondary) mutagenic effects; carcinogenic effects; acute toxicity; routes of entry; metabolic process; bis(ethylhexyl) phthalate; dioctyl phthalate; dimethyl phthalate; diethyl phthalate; diallyl phthalate; dibutyl phthalate; diisobutyl phthalate; excretion; animal experiments; teratogenic effects; chronic toxicity; cytotoxic effects; health hazards; literature survey
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Esters and salts
Genetic factors in reaction to exposures
Phthalates