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Document ID (ISN)19535
CIS number 73-137
ISSN - Serial title 0004-1254 - Arhiv za higijenu rada i toksikologiju
Year 1971
Convention or series no.
Author(s) Kuljak S., Stern P.
Title Protective effects of glutathione and xanthinol nicotinate against carbon disulphide poisoning in the mouse
Bibliographic information 1971, Vol.22, No.2, p.137-142. Illus. 11 ref.
Abstract Experiments with mice, which received 100mg glutathione per kg body weight and were then exposed to carbon disulfide inhalation at the acute LD50, showed that glutathione has a protective action. The same dose of xanthionol nicotinate, administered under similar conditions provided protection against the effects of CS2 inhalation. The mechanism of protective action for each substance is discussed and the differences highlighted.
Descriptors (primary) pharmacological prevention; toxicology; carbon disulfide
Descriptors (secondary) xanthinol nicotinate; animal experiments; antidote treatment; glutathione
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic sulfur compounds
Inorganic substances