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CISDOC database
| Document ID (ISN) | 18739 |
| CIS number |
73-1378 |
| ISSN - Serial title |
0002-8894 - American Industrial Hygiene Association Journal |
| Year |
1972 |
| Convention or series no. |
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| Author(s) |
Griffiths J.E. |
| Title |
Acute inhalation and dermal application screening studies of 2,4,6-trifluoro-sym-triazine and 2,4,6-tris (trifluoromethyl)-sym-triazine |
| Bibliographic information |
June 1972, Vol.33, No.6, p.382-388. 7 ref. |
| Abstract |
Screening tests for acute inhalation (rats) and dermal toxicity (rabbits) were carried out to evaluate the potential toxicity of 2,4,6-trifluoro-sym-triazine - (FCN)3, commonly known as cyanuric fluoride - and 2,4,6-tris (trifluoromethyl)-sym-triazine - (CF3CN)3 or TTT. The results are presented and discussed. Acute inhalation and acute percutaneous tests with cyanuric fluoride both revealed a high level of toxicity (estimated at LC50=3ppm and LD50=100µL/kg of body weight, respectively). The corresponding values for TTT were LC50=1400ppm and LD50>1000µL/kg. Cyanuric fluoride is particularly insidious: it passes through all layers of the skin and has the property of swelling rubber, so that rubber gloves do not afford adequate protection. Human response, however, cannot be predicted objectively from these tests. |
| Descriptors (primary) |
fluorinated organic compounds; triazines; skin absorption; inhalation; cyanuric fluoride |
| Descriptors (secondary) |
toxicity evaluation |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
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| Broad subject area(s) |
Chemical safety
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| Browse category(ies) |
Heterocyclic compounds
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