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Document ID (ISN)18696
CIS number 73-1377
ISSN - Serial title 0002-8894 - American Industrial Hygiene Association Journal
Year 1972
Convention or series no.
Author(s) Heistand R.N., Todd A.S.
Title Automated determination of total phenol in urine
Bibliographic information June 1972, Vol.33, No.6, p.378-381. Illus. 5 ref.
Abstract A fully automated method has been developed to determine total phenol in urine. The reagents include a buffer solution, sulphuric acid, 4-aminoantipyrine and an oxidant. The analytical procedure involves hydrolysis of conjugated phenols and steam distillation, followed by colorimetric phenol determination in the distillate. Urine samples (1-2mL) are run sequentially at the rate of 10 per hour; the precision obtained is 1.6ppm per litre. The method could be used routinely to assess benzene exposure.
Descriptors (primary) phenol; determination of concentration; determination in urine; automation
Descriptors (secondary) poisoning; benzene; chemical reactions; reagents; hydrolysis; determination in biological matter; chemical analysis; colorimetry; continuous sampling
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Phenols and phenolic compounds
Alcohols