|Document ID (ISN)||112440|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Zhang L., Ye F.L., Chen T., Mei Y., Song S.Z.
||Trans, trans-muconic acid as a biomarker of occupational exposure to high-level benzene in China
||Oct. 2011, Vol.53, No.10, p.1194-1198. Illus. 41 ref.
||Trans_trans-muconic_acid_[BUY_THIS_ARTICLE] [in English]
ILO_LABORDOC_[INTRANET_ACCESS] [in English]
||The work aimed to study the potential correlation between high-level benzene exposures and urinary benzene metabolites S-phenylmercapturic acid (SPMA) and trans, trans-muconic acid (t,t-MA) among Chinese shoe industry workers. Individual benzene-exposed levels were determined by gas chromatography analysis; urinary metabolites were determined by high performance liquid chromatography coupled with mass spectrometry. The concentration of benzene ranged from 2.57 to 146.11 mg/m3. The correlation between benzene and t,t-MA was significantly higher than that of SPMA at the postshift. It is concluded that t,t-MA is a more specific biomarker than SPMA at high-level benzene exposures.
||China; benzene; trans,trans-muconic acid; exposure tests; shoe industry
||determination in urine; exposure evaluation; reliability; description of technique
||D - Periodical articles
||Leather, fur and footwear
Toxic and dangerous substances
|Broad subject area(s)
Footwear, leather and fur industry