|Document ID (ISN)||112395|
|ISSN - Serial title
||1076-2752 - Journal of Occupational and Environmental Medicine
|Convention or series no.
||Lipworth L., Sonderman J.S., Mumma M.T., Tarone R.E., Marano D.E., Boice J.D, McLaughlin J.K.
||Cancer mortality among aircraft manufacturing workers - An extended follow-up
||Sep. 2011, Vol.53, No.9, p.992-1007. 33 ref.
||Cancer_mortality_[BUY_THIS_ARTICLE] [in English]
||In this extended cancer follow-up among 77,943 aircraft workers, comprehensive exposure information enabled detailed classification of trichloroethylene (TCE), perchloroethylene (PCE), mixed solvents and chromate exposures. Exposure to TCE, PCE, mixed solvents or chromates was not associated with increased cancer risk overall or for most cancer sites. Elevated rates compared with the general population were seen for non-Hodgkin lymphoma for PCE exposure, and colon and testicular cancers and multiple myeloma for mixed solvents exposure. Internal cohort analyses, however, showed no significant trends of increasing risk for these cancers with increasing years of exposure to TCE, PCE or mixed solvents. This large, long-term cohort study with comprehensive exposure assessment found no consistent evidence of increased cancer risk overall or by site among aircraft workers, including those with long-term exposure to TCE, PCE, and mixed solvents.
||mortality; cancer; aircraft industry; length of exposure; risk factors
||chromates; trichloroethylene; tetrachloroethylene; solvents; long-term study; cohort study
||D - Periodical articles
||Metal production and metalworking
Toxic and dangerous substances
|Broad subject area(s)
||Occupational medicine, epidemiology
||Aerospace manufacturing and maintenance industry
Cancer and carcinogens