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CISDOC database

Document ID (ISN)112394
CIS number 12-0155
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2011
Convention or series no.
Author(s) Kelly K.J., Wang M.L., Klancnik M., Petsonk E.L.
Title Prevention of IgE sensitization to latex in health care workers after reduction of antigen exposures
Bibliographic information Aug. 2011, Vol.53, No.8, p.934-940. 26 ref.
Internet access Prevention_of_IgE_sensitization_to_latex_[BUY_THIS_ARTICLE] [in English]
Abstract The objective of this study was to investigate occupational latex allergy in health care workers (HCWs) before and after an intervention designed to reduce latex allergen exposure from gloves. Latex antigen concentrations in work area air ducts were measured before the intervention. Symptoms and latex sensitization were monitored annually before and after the intervention in 805 HCWs, using questionnaires and skin prick testing. The prevalence of latex sensitization before the intervention correlated with air duct latex antigen measurements for HCWs exposed to low, intermediate and high antigen levels. After the intervention, new latex sensitization rates declined 16-fold, and 25% of previously sensitized employees reverted to negative skin tests. Airborne antigen exposure is a major source of latex sensitization among HCWs. Use of powder-free latex gloves markedly reduces the risk of sensitization.
Descriptors (primary) natural rubber; latex; allergens; sensitization; protective gloves; limitation of exposure; health care personnel; frequency rates
Descriptors (secondary) immunoglobulin changes; determination in blood; skin tests; questionnaire survey; programme evaluation
Document type D - Periodical articles
Subject(s) Commerce, services, offices
Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Allergies
Health care services