| Document ID (ISN) | 112278 |
| CIS number |
12-0033 |
| ISBN(s) |
978-3-7776-1474-8 |
| Year |
2006 |
| Convention or series no. |
BUA Report 251
|
| Author(s) |
Gesellschaft Deutscher Chemiker (GDCh), Advisory Committee on Existing Chemicals (BUA) |
| Title |
Benzanthrone |
| Bibliographic information |
Hirzel Verlag, Birkenwaldstrasse 44, 70191 Stuttgart, Germany, 2006. xv, 112p. Bibl.ref. Price: EUR 60.00. |
| Internet access |
BUA_Report_251_Summary_[INTERNET_FREE_ACCESS] [in English]
BUA_Report_251_[BUY_THIS_DOCUMENT].pdf [in English]
|
| Abstract |
Conclusions of this criteria document which reflects the state of knowledge as of April 2004: benzanthrone can be absorbed orally and by inhalation. It is of low acute toxicity (inhalation LC50 in the mouse is >5000 mg/m3; oral LD50 in the rat and guinea pig is >2000 mg/kg; dermal LD50 in the rabbit is >3000 mg/kg). In humans, target organs are the skin, nervous system, lung and liver. Benzanthone causes phototoxic dermatitis in humans, with photo-allergic reactions suspected in some cases. It is not mutagenic in the mutagenicity test with Salmonella typhimuriumstudies on the carcinogenic potential of benzanthrone are not available. Other findings are discussed. |
| Descriptors (primary) |
Germany; benzanthrone; toxicology; ecotoxicology |
| Descriptors (secondary) |
photosensitization dermatitis; animal experiments; literature survey; criteria document |
| Document type |
B - Chemical safety information sheets |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Toxicology
Aliphatic and alicyclic hydrocarbons
|
