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Document ID (ISN)112037
CIS number 11-0669
ISSN - Serial title 0033-3506 - Public Health
Year 2011
Convention or series no.
Author(s) Heinrich S., Peters A., Kellberger J., Ellenberg D., Genuneit J., Nowak D., Vogelberg C., von Mutius E., Weinmayr G., Radon K.
Title Study on occupational allergy risks (SOLAR II) in Germany: Design and methods
Bibliographic information 2011, Vol.11, No.298, 11 p. (Internet document).
Internet access Study_on_occupational_allergy_risks.pdf [in English]
Abstract SOLAR II is the 2nd follow-up of a population-based cohort recruited in Munich and Dresden in 1995/6. A first follow-up study was conducted 2002 and 2003 (SOLAR I). The aims of SOLAR II were to investigate the course of atopic diseases over puberty taking environmental and occupational risk factors into account. This article describes the methods of the 2nd follow-up carried out from 2007 to 2009 and the challenges faced while studying a population-based cohort of young adults. Wherever possible, the same questionnaire instruments were used throughout the studies. They included questions on respiratory and allergic diseases, domestic and occupational exposure and work related stress. Furthermore, clinical examinations including skin prick tests, spirometry and bronchial challenge with methacholine, exhaled nitric oxide and blood samples were employed at baseline and 2nd follow-up. Of the 3053 SOLAR I study participants who had agreed to be contacted again, about 50% had moved in the meantime and had to be traced using phone directories and the German population registries. Overall, 2904 of these participants could be contacted on average five years after the first follow-up. From this group, 2051 subjects (71%) completed the questionnaire they received via mail. Of these, 57% participated at least in some parts of the clinical examinations. Challenges faced included the high mobility of this age group. Time constraints and limited interest in the study were substantial. Analysing the results, selection bias had to be considered as questionnaire responders (54%) and those participating in the clinical part of the study (63%) were more likely to have a high parental level of education compared to non-participants (42%). Similarly, a higher prevalence of parental atopy (such as allergic rhinitis) at baseline was found for participants in the questionnaire part (22%) and those participating in the clinical part of the study (27%) compared to non-participants (11%).
Descriptors (primary) Germany; occupational diseases; allergies; young persons; risk factors
Descriptors (secondary) long-term study; questionnaire survey; cohort study; reliability; individual susceptibility; social aspects
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Allergies
Young workers