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CISDOC database

Document ID (ISN)112025
CIS number 11-0696
ISSN - Serial title 0962-7480 - Occupational Medicine
Year 2010
Convention or series no.
Author(s) Zakeri F., Hirobe T., Akbari Noghabi K.
Title Biological effects of low-dose ionizing radiation exposure on interventional cardiologists
Bibliographic information Sep. 2010, Vol.60, No.6, p.464-469. Illus. 26 ref.
Internet access Biological_effects.pdf [in English]
Abstract Interventional cardiologists (ICs) are likely to receive high radiation exposure as a result of procedures they undertake. The objective of this study was to assess the effects of low-dose X-ray radiation exposure on chromosomal damage and on selected indices of cellular and humoral immunity in ICs. The study population consisted of 37 ICs and 37 clinical physicians as the control group with similar age, sex and duration of employment, without any work-related exposure to ionizing radiation. Cytogenetic studies were performed by chromosome aberration analysis and immunological studies by flow cytometry, enzyme-linked immunosorbent assay and immunodiffusion techniques. The frequencies of aberrant cells, chromosome breaks and dicentrics plus centric rings were significantly higher in the exposed group compared to the control group, without positive correlation between the frequency of dicentric and centric ring aberrations and the cumulative doses of the ICs. Other findings are discussed.
Descriptors (primary) ionizing radiation; x-rays; health care personnel; chromosome changes; cytotoxic effects; risk factors
Descriptors (secondary) Iran, Islamic Republic of; lymphocytes; determination in blood; case-control study; hospitals
Document type D - Periodical articles
Subject(s) Commerce, services, offices
Broad subject area(s) Physical hazards
Occupational medicine, epidemiology
Browse category(ies) Ionizing radiation
Health care services
Genetic factors in reaction to exposures