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CISDOC database
| Document ID (ISN) | 111899 |
| CIS number |
11-0506 |
| ISSN - Serial title |
1351-0711 - Occupational and Environmental Medicine |
| Year |
2010 |
| Convention or series no. |
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| Author(s) |
Heck J.E., Charbotel B., Moore L.E., Karami S., Zaridze D.G., Matveev V., Janout V., Kollárová H., Foretova L., Bencko V., Szeszenia-Dabrowska N., Lissowska J., Mates D., Ferro G., Chow W.H., Rothman N., Stewart P., Brennan P., Boffetta P. |
| Title |
Occupation and renal cell cancer in Central and Eastern Europe |
| Bibliographic information |
Jan. 2010, vol.67, No.1, p.47-53. 42 ref. |
| Abstract |
Central and Eastern Europe has among the highest rates of renal cell cancer worldwide. Few studies have been conducted in these areas to investigate the possible role of occupational exposures in renal cell cancer aetiology. The purpose of this study was to examine the association of renal cell cancer with employment in specific occupations and industries. From 1999 to 2003, a hospital-based case-control study was conducted in seven areas of the Czech Republic, Poland, Romania and Russia. A detailed occupational history was collected from renal cell cancer cases and controls, together with information on potential confounders. Odds ratios (ORs) of cancer risk were calculated for having ever been employed in selected jobs and industries, with follow-up analyses examining duration of employment. A total of 992 histologically-confirmed incident renal cell cancer cases and 1459 controls were included in the analysis. An increased risk of renal cell cancer was observed for workers in agricultural labour and animal husbandry (OR 1.43), particularly among women employed as general farm workers (OR 2.73). Risk gradients for agricultural work increased with longer employment. An overall increased risk of renal cell cancer was seen among architects and engineers (OR 1.89), and mechanical engineers (OR 1.71). |
| Descriptors (primary) |
Eastern Europe; epidemiology; occupation disease relation; renal cancer; job-exposure relation; risk factors |
| Descriptors (secondary) |
Czech Republic; Poland; Romania; Russian Federation; diagnosis; length of service; histopathology; case-control study; statistical evaluation; length of exposure |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
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| Broad subject area(s) |
Occupational medicine, epidemiology
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| Browse category(ies) |
Cancer and carcinogens
Diseases of the kidney and the urinary system
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