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Document ID (ISN)111895
CIS number 11-0503
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2010
Convention or series no.
Author(s) Aguilar-Madrid G., Robles-Pérez E., Juárez-Pérez C.A., Alvarado-Cabrero I., Rico-Méndez F.G., Javier K.G.
Title Case-control study of pleural mesothelioma in workers with social security in Mexico
Bibliographic information 2010, Vol.53, p.241-251. Illus. 61 ref.
Abstract Environmental and occupational exposure to asbestos in Mexico in the past has been a cause of deaths and health damages. Its magnitude is unknown to date. The objective of this study was to identify the proportion of cases of malignant pleural mesothelioma (MPM) that can be attributed to and occupational exposure to asbestos. It was conducted in the form of a case-control study of MPM in 472 workers insured by the Mexican Institute of Social Security, with 119 incident cases and 353 controls. Cases were histologically confirmed. Participants were questioned concerning their occupational history and socio-demographic data. Assignment to one of the four exposures was performed qualitatively by an expert hygienist. Odds ratios (ORs) and attributable risks (ARs) were calculated using a non-conditional logistic regression model. A total of 80.6% of cases and 31.5% of controls had occupational exposure to asbestos. ORs were adjusted for age and gender and by exposure category, and exhibited an increase with probability of exposure. These results show that the industrial uses of all forms of asbestos is generating an increase in mesothelioma-related diseases and deaths among Mexican workers. As a public health policy, Mexico should prohibit the use of asbestos in all production processes with the aim of controlling the epidemic and preventing the occurrence of new cases of MPM.
Descriptors (primary) Mexico; asbestos; pleural mesothelioma; risk factors
Descriptors (secondary) diagnosis; histopathology; case-control study
Document type D - Periodical articles
Subject(s) Occupational pathology
Toxic and dangerous substances
Broad subject area(s) Occupational medicine, epidemiology
Chemical safety
Browse category(ies) Cancer and carcinogens