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Document ID (ISN)111307
CIS number 10-0806
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2011
Convention or series no.
Author(s) Teschke K., Abanto Z., Arbour L., Beking K., Chow Y., Gallagher R.P., Jong B., Le N.D., Ratner P.A., Spinelli J.J., Dimich-Ward H.
Title Exposure to anesthetic gases and congenital anomalies in offspring of female registered nurses
Bibliographic information 2011, Vol.54, p.118-127. Illus. 40 ref.
Abstract This retrospective cohort study was carried out to examine associations between congenital anomalies in offspring and anesthetic gas exposure of mothers employed as nurses. A cohort of registered nurses in British Columbia, Canada, was linked to records of births and congenital anomalies from 1990 to 2000. Exposures were assessed via a survey of anesthetic gas use in all hospitals in the province and records of nurses' jobs, departments, and hospitals. Departments most frequently reporting anesthetic gas use were operating rooms, post-anesthetic recovery rooms and maternity units. In the cohort of 15,317 live-borne children of 9,433 mothers, 1,079 had congenital anomalies. Anomalies were associated with proven and probable maternal exposure to halogenated gases and to nitrous oxide.
Descriptors (primary) British Columbia; inhalation anaesthetics; women; hospitals; nursing personnel; teratogenic effects; risk factors
Descriptors (secondary) Canada; nitrous oxide; halothane; isoflurane; cohort study
Document type D - Periodical articles
Country / State or ProvinceBritish Columbia
Subject(s) Toxic and dangerous substances
Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Industries and occupations
Chemical safety
Browse category(ies) Cancer and carcinogens