|Document ID (ISN)||111271|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Pira E., Pelucchi C., Piolatto P.G., Negri E., Bilei T., La Vecchia C.
||Mortality from cancer and other causes in the Balangero cohort of chrysotile asbestos miners
||Dec. 2009, Vol.66, No.12, p.805-809. 33 ref.
||The objective of this study was to provide further information on mortality from cancer and other causes among chrysotile asbestos miners several years after exposure ceased, updating the analyses from the Balangero mine worker cohort with follow-up to the end of 2003. The cohort included 1056 men, for a total of 34,432 man-years of observation. Employment data were obtained from personnel records, the vital status and causes of death were obtained through population registers and death certificates from municipal registration offices. Expected numbers of deaths and standardized mortality ratios (SMRs) were computed for relevant causes using the province of Turin and national death rates, for each 5-year calendar period and age group. Significant excess mortality was found from pleural cancer only (4 deaths, SMR 4.67) and pleural and peritoneal cancers combined (5 deaths, SMR 3.16). All pleural and peritoneal cancer deaths occurred 30 or more years after first exposure. The SMRs were 1.27 for lung cancer (45 deaths), 1.82 for laryngeal cancer (8 deaths) and 1.12 for all cancers (142 deaths). Cumulative dust exposure and the various time factors considered did not show a clear pattern of risk associated with mortality from lung cancer. There were 57 deaths from cirrhosis (SMR 2.94) and 54 from accidents and violence (SMR 1.88). Overall, 590 deaths were observed as compared to 412.9 expected (SMR 1.43).
||chrysotile; mortality; cancer; asbestos mining; risk factors
||Italy; alcoholism; peritoneal mesothelioma; lung cancer; pleural mesothelioma; exposure evaluation; cohort study; statistical evaluation
||D - Periodical articles
Mines and quarries
Toxic and dangerous substances
|Broad subject area(s)
Occupational medicine, epidemiology
Mining and quarrying
Cancer and carcinogens