| Document ID (ISN) | 110422 |
| CIS number |
09-1302 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
2009 |
| Convention or series no. |
|
| Author(s) |
Hsiao P.K., Lin Y.C., Shih T.S., Chiung Y.M. |
| Title |
Effects of occupational exposure to 1,4-dichlorobenzene on hematologic, kidney, and liver functions |
| Bibliographic information |
Oct. 2009, Vol.82, No.9, p.1077-1085. Illus. 34 ref. |
| Abstract |
The objective of this study was to investigate the effects of 1,4-dichlorobenzene (1,4-DCB) on kidney, liver and haematological functions of workers in insect repellent factories in Taiwan. It involved 46 exposed workers and 29 non-exposed workers. Health information was collected using questionnaires and biochemical tests. The concentration of urinary 2,5-dichlorophenol (2,5-DCP), the major metabolite of 1,4-DCB, was analyzed by gas chromatography with electron-capture detection. Exposed workers had higher urinary 2,5-DCP concentrations (105.38µg/L) than controls (1.08µg/L). Exposure to 1,4-DCB also increased the white blood cell count and serum alanine aminotransferase level. Other findings are discussed. |
| Descriptors (primary) |
chemical industry; exposure tests; p-dichlorobenzene; Taiwan (China) |
| Descriptors (secondary) |
blood count; transaminases; questionnaire survey; case-control study; urinary metabolites; 2,5-dichlorophenol; liver function tests; renal function tests; gas chromatography; determination in urine; haematological effects |
| Document type |
D - Periodical articles |
| Country / State or Province | Taiwan (China) |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Chemical industry
Biological monitoring
Halogenated hydrocarbons
|
