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CISDOC database

Document ID (ISN)110253
CIS number 09-1329
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2009
Convention or series no.
Author(s) Broding H.C., Michalke B., G÷en T., Drexler H.
Title Comparison between exhaled breath condensate analysis as a marker for cobalt and tungsten exposure and biomonitoring in workers of a hard metal alloy processing plant
Bibliographic information Apr. 2009, Vol.82, No.5, p.565-573. Illus. 75 ref.
Abstract Cobalt (Co), tungsten (W) and tungsten carbides (WC) are major constituents of hard metal alloys. This study examined the feasibility of using exhaled breath condensate (EBC) as an alternative to urinary determinations for evaluating exposures to Co and W. A total of 62 subjects were recruited from a hard metal processing plant in Germany. Examinations included the airborne workplace concentrations, spirometry, and determinations of Co and W in EBC and urine. It is concluded that urinary concentrations of Co and W remain more reliable indicators of current workplace exposure than EBC concentrations. Other findings are discussed.
Descriptors (primary) cobalt and compounds; tungsten and compounds; determination in urine; exposure tests; determination in exhaled air; medical supervision
Descriptors (secondary) tungsten carbide 1:1; mass spectrometry; Germany; alloys; plasma emission spectrometry; breathing atmosphere; determination in air; atomic absorption spectrometry; description of technique; reliability
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Biological monitoring