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Document ID (ISN)110173
CIS number 09-1115
ISSN - Serial title 0019-8366 - Industrial Health
Year 2009
Convention or series no.
Author(s) Nishimura S., Yasui H., Miyauchi H., Kikuchi Y., Kondo N., Takebayashi T., Tanaka S., Mikoshiba Y., Omae K., Nomiyama T.
Title A cross-sectional observation of effect of exposure to N-methyl-2-pyrrolidone (NMP) on workers' health
Bibliographic information July 2009, Vol.47, No.4, p.355-362. Illus. 35 ref.
Abstract This study was aimed at clarifying the effect of exposure to N-methyl-2-pyrrolidone (NMP) on workers' health. Fifteen male NMP-exposed workers and 15 referent male workers were recruited for this study. Exposure concentrations were assessed by determining NMP in the breathing zones and urinary NMP. Clinical examinations, motor nerve conduction velocities in the dominant arm and neurobehavioral tests were carried out. Subjects were also asked to complete self-administered questionnaires for subjective symptoms and psychological assessment. There were neither dose-dependent changes nor any differences between NMP-exposed and referent workers in terms of clinical data, motor nerve conduction, neurobehavioral responses and subjective symptoms.
Descriptors (primary) male workers; Japan; methylpyrrolidinone; risk factors; health hazards
Descriptors (secondary) subjective assessment; anxiety; depressive neurosis; questionnaire survey; cross-sectional study; determination in urine; conduction velocity; breathing atmosphere; determination in air; medical examinations; nervous conduction
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Heterocyclic compounds