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Document ID (ISN)109784
CIS number 09-884
ISSN - Serial title 0944-2502 - Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie
Year 2008
Convention or series no.
Author(s) Müller M., Bode M., Behrendt B., Dillmann U., Fassbender K., Buchter A.
Title Chronic diseases due to perchloroethene - Clinical picture and course
Original title Chronische Erkrankungen durch Perchlorethen - Klinisches Bild und Verlauf [in German]
Bibliographic information Jan. 2008, Vol.58, No.1, p.4-19. 48 ref.
Abstract The medical files of ten patients who developed a chronic-toxic encephalopathy (stage III for eight patients and stage II b for two patients) and other diseases as a result of exposure to perchloroethene were examined. The follow-up conducted after 15 years did not show any significant improvements of the deficits. On the contrary, despite the fact that exposure had ceased, progressive worsening was observed, three patients having died soon after the beginning of the follow-up. Hence, the progress of chronic-toxic encephalopathy is most likely even after the cessation of exposure.
Descriptors (primary) toxic effects; encephalopathy; hexachloroethane
Descriptors (secondary) Germany; neurological effects; long-term study
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the nervous system
Halogenated hydrocarbons