ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)109372
CIS number 09-396
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2009
Convention or series no.
Author(s) Sobus J.R., Waidyanatha S., McClean M.D., Herrick R.F., Smith T.J., Garshick E., Laden F., Hart J.E., Zheng Y., Rappaport S.M.
Title Urinary naphthalene and phenanthrene as biomarkers of occupational exposure to polycyclic aromatic compounds
Bibliographic information Feb. 2009, Vol.66, No.2, p.99-104. Illus. 25 ref.
Abstract This study investigated the utility of unmetabolised naphthalene (Nap) and phenanthrene (Phe) in urine as biomarkers of exposures to mixtures of polycyclic aromatic hydrocarbons (PAHs). It involved 39 workers exposed to diesel exhausts (low PAH exposure level), 26 exposed to emissions from asphalt (medium PAH exposure level) and 28 exposed to emissions from coke ovens (high PAH exposure level). Levels of Nap and Phe were measured in urine from each subject. Published levels of airborne Nap, Phe and other PAHs in the relevant sectors were taken into account. Data were subjected to statistical evaluation. It was found that levels of Nap and Phe in urine reflected the workplace atmospheric concentrations of these compounds and therefore constitute promising surrogates for occupational exposures to PAH mixtures.
Descriptors (primary) diesel engines; phenanthrene; aromatic hydrocarbons; coke oven gas; naphthalene; bitumen; polycyclic hydrocarbons; exposure tests; exhaust gases
Descriptors (secondary) mass spectrometry; reliability; exposure evaluation; breathing atmosphere; determination in urine; determination in air; description of technique; gas chromatography; statistical evaluation
Document type D - Periodical articles
Country / State or ProvinceChina; USA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Biological monitoring
Polycyclic hydrocarbons
Aromatic hydrocarbons