|Document ID (ISN)||109372|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Sobus J.R., Waidyanatha S., McClean M.D., Herrick R.F., Smith T.J., Garshick E., Laden F., Hart J.E., Zheng Y., Rappaport S.M.
||Urinary naphthalene and phenanthrene as biomarkers of occupational exposure to polycyclic aromatic compounds
||Feb. 2009, Vol.66, No.2, p.99-104. Illus. 25 ref.
||This study investigated the utility of unmetabolised naphthalene (Nap) and phenanthrene (Phe) in urine as biomarkers of exposures to mixtures of polycyclic aromatic hydrocarbons (PAHs). It involved 39 workers exposed to diesel exhausts (low PAH exposure level), 26 exposed to emissions from asphalt (medium PAH exposure level) and 28 exposed to emissions from coke ovens (high PAH exposure level). Levels of Nap and Phe were measured in urine from each subject. Published levels of airborne Nap, Phe and other PAHs in the relevant sectors were taken into account. Data were subjected to statistical evaluation. It was found that levels of Nap and Phe in urine reflected the workplace atmospheric concentrations of these compounds and therefore constitute promising surrogates for occupational exposures to PAH mixtures.
||diesel engines; phenanthrene; aromatic hydrocarbons; coke oven gas; naphthalene; bitumen; polycyclic hydrocarbons; exposure tests; exhaust gases
||mass spectrometry; reliability; exposure evaluation; breathing atmosphere; determination in urine; determination in air; description of technique; gas chromatography; statistical evaluation
||D - Periodical articles
|Country / State or Province||China; USA|
||Toxic and dangerous substances
|Broad subject area(s)