ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)109302
CIS number 09-295
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2007
Convention or series no.
Author(s) Santibáñez M., Bolumar F., García A.M.
Title Occupational risk factors in Alzheimer's disease: A review assessing the quality of published epidemiological studies
Bibliographic information Nov. 2007, Vol.64, No.11, p.723-732. Illus. 43 ref.
Abstract Epidemiological evidence of an association between Alzheimer's disease (AD) and the most frequently studied occupational exposures, namely pesticides, solvents, electromagnetic fields (EMF), lead and aluminium, is inconsistent. Epidemiological studies published up to June of 2003 were systematically searched through PubMed and Toxline. Twenty-four studies (21 case-control and 3 cohort studies) were included. The quality of the studies was assessed. Eleven studies explored the relationship of AD with solvents, seven with EMF, six with pesticides, six with lead and three with aluminium. For pesticides, studies of greater quality and prospective design found increased and statistically significant associations. For the remaining occupational agents, the evidence of association is less consistent (for solvents and EMF) or absent (for lead and aluminium).
Descriptors (primary) electromagnetic fields; risk factors; epidemiology
Descriptors (secondary) epidemiological aspects; lead and compounds; aluminium and compounds; computerized data bases; pesticides; solvents; evaluation of results; Alzheimer's disease
Document type D - Periodical articles
Country / State or ProvinceSpain
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Electromagnetic fields