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Document ID (ISN)109165
CIS number 09-88
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2008
Convention or series no.
Author(s) Apfelbacher C.J., Radulescu M., Diepgen T.L., Funke U.
Title Occurrence and prognosis of hand eczema in the car industry: Results from the PACO follow-up study (PACO II)
Bibliographic information June 2008, Vol.58, No.6, p.322-329. Illus. 23 ref.
Abstract The aim of the Prospective Audi Cohort (PACO) II follow-up study was to estimate the burden and prognosis of hand eczema (HE) in an automobile industry setting in a long-term perspective (> 10 years). Eligible participants were 1909 subjects who had been examined in a previous study and had been followed through until the end of their apprenticeship. Participants were interviewed and underwent dermatological examination. An exposure assessment was carried out according to a pre-defined algorithm. The follow-up rate was 78.3%. Mean follow-up time was 13.3 years and the cumulative incidence of 29.3% for the entire study period. HE persisted after the end of apprenticeship in 40.0% of subjects who had had HE during apprenticeship. 18.0% developed HE in the follow-up period. Around 30% of subjects were affected by HE at least once during the study period.
Descriptors (primary) eczema; motor vehicle industry; hand
Descriptors (secondary) Germany; prognosis; dermatitis; frequency rates; long-term study; apprentices; cohort study
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Metal production and metalworking
Broad subject area(s) Industries and occupations
Occupational medicine, epidemiology
Browse category(ies) Motor vehicle manufacturing industry
Skin diseases