| Document ID (ISN) | 109127 |
| CIS number |
09-37 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2008 |
| Convention or series no. |
|
| Author(s) |
Yucesoy B., Kurzius-Spencer M., Johnson V.J., Fluharty K., Kashon M.L., Guerra S., Luster M.I., Burgess J.L. |
| Title |
Association of cytokine gene polymorphisms with rate of decline in lung function |
| Bibliographic information |
June 2008, Vol.50, No.6, p.642-648. 37 ref. |
| Abstract |
The objective of this study was to investigate whether genetic variants involved in cytokine expression are associated with the age-related rate of decline in one-second forced expiratory volume (FEV1). Gene polymorphisms were investigated in 374 active firefighters for whom the data of at least five pulmonary function tests were available. Findings are discussed. It is concluded that inter-individual variability in progressive decline in FEV1 may be explained in part by genetic variations within genes involved in inflammatory responses. |
| Descriptors (primary) |
fire fighting; genetic effects; pulmonary function |
| Descriptors (secondary) |
USA; DNA; individual susceptibility; respiratory function tests; age-linked differences; one-second forced expiratory volume |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Occupational medicine, epidemiology
|
| Browse category(ies) |
Antifertility and prenatal effects
Fires
Genetic factors in reaction to exposures
|
