| Document ID (ISN) | 109122 |
| CIS number |
09-159 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2008 |
| Convention or series no. |
|
| Author(s) |
Symons J.M., Kreckmann K.H., Sakr C.J., Kaplan A.M., Leonard R.C. |
| Title |
Mortality among workers exposed to acrylonitrile in fiber production: An update |
| Bibliographic information |
May 2008, Vol.50, No.5, p.550-560. Illus. 56 ref. |
| Abstract |
This study updates the mortality experience through 2002 for a cohort of workers of a large United States chemical company exposed to acrylonitrile (AN). Standardized mortality ratios were estimated based on two reference populations: the United States population and an employee population from the same regions as the plants. Exposure-response analyses were conducted using Cox regression models for cumulative and mean intensity exposure measures. In the cohort of 2548 workers, 839 deaths have occurred with 91 deaths due to respiratory system cancer. Most standardized mortality ratios were at or near no-effects levels. Hazard ratios (HR) indicated no increased mortality risk for respiratory system cancer (adjusted HR = 0.96). |
| Descriptors (primary) |
synthetic fibre industry; chemical industry; risk factors; mortality; polyacrylonitrile |
| Descriptors (secondary) |
USA; acrylonitrile; respiratory diseases; statistical evaluation; exposure evaluation; cohort study; cancer |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Chemicals, plastics and rubber
|
| Broad subject area(s) |
Chemical safety
Occupational medicine, epidemiology
|
| Browse category(ies) |
Chemical industry
|
