|
|
|
|
CISDOC database
Document ID (ISN) | 109100 |
CIS number |
09-127 |
ISSN - Serial title |
0019-8366 - Industrial Health |
Year |
2008 |
Convention or series no. |
|
Author(s) |
Ohbayashi H., Saito M., Senoh H., Umeda Y., Aiso S., Yamazaki K., Nagano K., Yamamoto S., Fukushima S. |
Title |
Occurrence of two different types of glutathione S-transferase placental form-positive hepatocytes after a single administration of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats |
Bibliographic information |
May 2008, Vol.46, No.3, p.281-288. Illus. 40 ref. |
Abstract |
Occurrence of glutathione S-transferase placental form (GST-P)-positive hepatocytes was examined, using 15 Wistar rats of both sexes each orally administered 2,3,7,8-tetrabromo-dibenzo-p-dioxin (TBDD) by gavage at a single dose of 0, 10, 30, 100 or 300 µ/kg body weight. Liver tissues were stained with anti-GST-P antibody. The characteristics of the two types of GST-P-positive hepatocytes which were found in the TBDD-dosed rat are discussed. |
Descriptors (primary) |
liver; glutathione transferase; tetrabromodibenzodioxin |
Descriptors (secondary) |
antibodies; microscopic determination; animal experiments |
Document type |
D - Periodical articles |
Country / State or Province | Japan |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Heterocyclic compounds
|
|
|
|
|
|