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Document ID (ISN)108917
CIS number 08-1380
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 2008
Convention or series no.
Author(s) Ferrari M., Negri S., Zadra P., Ghittori S., Imbriani M.
Title Saliva as an analytical tool to measure occupational exposure to toluene
Bibliographic information Aug. 2008, Vol.81, No.8, p.1021-1028. Illus. 19 ref.
Abstract Biomonitoring of toluene exposure is commonly performed using blood or urine sampling. Sampling of saliva may be a simple and a viable alternative. In this study, solvent concentrations in urine and saliva were measured in a group of 36 workers exposed to toluene in the synthetic leather industry. Their environmental exposure to toluene was assessed using passive samplers. Toluene in urine, saliva and environmental samples was measured by GC-MS. Environmental toluene levels ranged from 0.22 to 57.20mg/m3, while the concentrations of the solvent in saliva and urine ranged from 0.12 to 18.30µg/L and from 0.47 to 26.64µg/L, respectively. The correlation coefficients between biological and environmental levels of toluene were 0.77 and 0.93, respectively, for saliva and urine samples. These findings suggest that saliva monitoring could be a simple and practical method of evaluating exposure to toluene.
Descriptors (primary) toluene; exposure tests; plastics converting industry; solvents
Descriptors (secondary) determination in saliva; reliability; exposure evaluation; determination in urine; determination in air; description of technique; statistical evaluation
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aromatic hydrocarbons
Biological monitoring