|Document ID (ISN)||108917|
|ISSN - Serial title
||0340-0131 - International Archives of Occupational and Environmental Health
|Convention or series no.
||Ferrari M., Negri S., Zadra P., Ghittori S., Imbriani M.
||Saliva as an analytical tool to measure occupational exposure to toluene
||Aug. 2008, Vol.81, No.8, p.1021-1028. Illus. 19 ref.
||Biomonitoring of toluene exposure is commonly performed using blood or urine sampling. Sampling of saliva may be a simple and a viable alternative. In this study, solvent concentrations in urine and saliva were measured in a group of 36 workers exposed to toluene in the synthetic leather industry. Their environmental exposure to toluene was assessed using passive samplers. Toluene in urine, saliva and environmental samples was measured by GC-MS. Environmental toluene levels ranged from 0.22 to 57.20mg/m3, while the concentrations of the solvent in saliva and urine ranged from 0.12 to 18.30µg/L and from 0.47 to 26.64µg/L, respectively. The correlation coefficients between biological and environmental levels of toluene were 0.77 and 0.93, respectively, for saliva and urine samples. These findings suggest that saliva monitoring could be a simple and practical method of evaluating exposure to toluene.
||toluene; exposure tests; plastics converting industry; solvents
||determination in saliva; reliability; exposure evaluation; determination in urine; determination in air; description of technique; statistical evaluation
||D - Periodical articles
|Country / State or Province||Italy|
||Toxic and dangerous substances
|Broad subject area(s)