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Document ID (ISN)108858
CIS number 08-1289
ISSN - Serial title 0339-6517 - Documents pour le médecin du travail
Year 2008
Convention or series no. DMT 114 TC 120
Author(s) Wild P., Bourgkard E., Paris C.
Title Lung cancer and occupational exposure to metals: Review of epidemiological studies
Original title Cancer du poumon et exposition professionnelle aux métaux: une revue des études épidémiologiques [in French]
Bibliographic information June 2008, No.114, p.201-219. Illus. 160 ref.
Internet access http://www.dmt-prevention.fr/inrs-pub/inrs01.nsf/IntranetObject-accesParReference/TC%20120/$File/TC120.pdf [in French]
Abstract This literature survey discusses epidemiological findings concerning the relationship between lung cancer and occupational exposure to metals. Epidemiological data are briefly reviewed for the following known carcinogens: chromium, nickel, beryllium, cadmium, arsenic and silicon (in the form of crystalline silica), highlighting some of the aspects that are still not fully understood. Next, it examines in greater detail some of the metals for which the link between exposure and lung cancer risk is less certain, namely titanium, lead, iron, cobalt and tungsten. Despite a high risk of bronchopulmonary cancer among certain populations exposed to lead, there does not appear to be any dose-response relationship. Epidemiological studies carried out in the hard metal industry suggest a possible carcinogenic risk from cobalt in the presence of tungsten carbide. Other findings are discussed.
Descriptors (primary) metals; risk factors; lung cancer; epidemiology
Descriptors (secondary) tungsten carbide 1:1; chromium; cadmium and compounds; iron and compounds; iron; cobalt and compounds; cobalt; nickel and compounds; nickel; tungsten and compounds; tungsten; arsenic and compounds; arsenic; lead and compounds; lead; beryllium and compounds; beryllium; silica; cadmium; titanium and compounds; titanium; chromium and compounds; literature survey
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Inorganic substances
Epidemiology