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Document ID (ISN)108656
CIS number 08-1066
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2008
Convention or series no.
Author(s) Sun Y., Sun D., Zhou Z., Zhu G., Zhang H., Chang X., Lei L., Jin T.
Title Osteoporosis in a Chinese population due to occupational exposure to lead
Bibliographic information June 2008, Vol.51, No.6, p.436-442. Illus. 28 ref.
Abstract The objective of this study was to investigate whether occupational lead exposure was associated with low bone mass in a population working in a storage battery plant. A total of 249 persons (191 men and 58 women) completed a questionnaire on various demographic, personal and job-related factors. Monophoton absorptiometry was used to measure bone mineral density (BMD). Urinary (UPb) and blood (BPb) lead concentrations were determined by graphite-furnace atomic absorption spectrophotometry. The BMD was significantly decreased in the groups of the high UPb compared with the low UPb level in both genders. The prevalence of osteoporosis was significantly related to the increase of both UPb and BPb. There was a dose-response relationship between lead exposure and prevalence of osteoporosis. Other findings are discussed.
Descriptors (primary) China; lead and compounds; risk factors; osteoporosis; battery and dry cell manufacture; lead
Descriptors (secondary) bone mineral density; questionnaire survey; sex-linked differences; dose-response relationship; absorption spectrometry; determination in blood; frequency rates; determination in urine; sampling and analysis
Document type D - Periodical articles
Country / State or ProvinceChina
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Occupational medicine, epidemiology
Browse category(ies) Diseases of the musculoskeletal system
Manufacturing of electrical appliances and equipment
Lead and compounds
Inorganic substances