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CISDOC database

Document ID (ISN)108347
CIS number 08-766
Year 2007
Convention or series no.
Agency for Toxic Substances and Disease Registry (ATSDR)
Title Toxicological profile for benzene (Update)
Bibliographic information U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Division of Toxicology/Toxicology Information Branch, 1600 Clifton Road NE, E-29, Atlanta, GA 30333, USA, Aug. 2007. xx, 382p. Illus. Approx. 1000 ref. Index.
Internet access [in English]
Abstract This profile has been prepared in accordance with guidelines set by the US Agency for Toxic Substances and Disease Registry and the EPA. The key literature related to the toxic effects of benzene is identified and reviewed. Contents: public health statement; health effects; chemical and physical information; production, import, use and disposal; potential for human exposure; analytical methods; regulations and advisories; glossary. Health hazards include: irritation of the eyes and skin; neurotoxic effects; bone marrow disorders (blood-cell anomalies); immunotoxic effects; mutagenic effects (chromosome changes); damage to the female reproductive system; carcinogenic effects (leukaemia). IARC has classified benzene in group 1 (carcinogenic to humans). (Update of CIS 99-1287).
Descriptors (primary) USA; benzene; health hazards; toxicity evaluation; toxicology
Descriptors (secondary) mutagenic effects; criteria document; neurotoxic effects; literature survey; antifertility effects; leukaemia; IARC; blood-cell anomalies; irritation; bone marrow diseases; skin absorption; limitation of exposure; exposure evaluation; chromosome changes; carcinogenic effects; immunotoxic effects; glossary; toxic effects
Document type B - Chemical safety information sheets
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aromatic hydrocarbons
Genetic factors in reaction to exposures