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Document ID (ISN)108282
CIS number 08-824
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2008
Convention or series no.
Author(s) Setta J.H., Neder A., Bagatin E., Terra-Filho M., Maris Nápolis L., Dal Corso S., Ferreira Amorin M.M., Tavares Rodrigues R., Godoy Fernandes A.L., Nery L.E.
Title Relationship between induced sputum cytology and inflammatory status with lung structural and functional abnormalities in asbestosis
Bibliographic information Mar. 2008, Vol.51, n°3, p.186-194. Illus. 41 ref.
Abstract In order to assess whether induced sputum cytology and local and systemic markers of inflammation may be helpful to characterize asbestosis status and progression, 39 ex-workers with asbestosis on high-resolution computed tomography and 21 non-exposed controls were evaluated. Sputum cytology and interleukin-8 (IL-8) in serum and sputum were related to lung function impairment. It was found that subjects with asbestosis had cytological abnormalities in induced sputum and increased local and systemic inflammatory status which were correlated to lung function impairment.
Descriptors (primary) asbestos; expectoration; inflammations; diagnosis; asbestosis
Descriptors (secondary) macrophages; determination in saliva; Brazil; interleukins; cytology; respiratory function tests; sampling and analysis; description of technique; case-control study
Document type D - Periodical articles
Country / State or ProvinceBrazil
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Asbestos
Pneumoconioses
Diseases of the respiratory system (except for pneumoconiosis & similar)