ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)107798
CIS number 08-403
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2006
Convention or series no.
Author(s) Pronk A., Yu F., Vlaanderen J., Tielemans E., Preller L., Bobeldijk I., Deddens J.A., Latza U., Baur X., Heederik D.
Title Dermal, inhalation and internal exposure to 1,6-HDI and its oligomers in car body repair shop workers and industrial spray painters
Bibliographic information Sep. 2006, Vol.63, No.9, p.624-631. Illus. 37 ref.
Abstract The objective of this study was to evaluate exposure to hexamethylene diisocyanate (HDI) and its oligomers among car body repair shop workers and industrial spray painters. A total of 95 personal samples were collected from six car body repair shops and five industrial paint shops and analysed using impingers with di-n-butylamine (DBA) in toluene. In parallel, dermal exposure was assessed using nitrile rubber gloves submerged into a solution of DBA in toluene after sampling. Analysis for HDI and its oligomers was performed by liquid chromatography coupled with mass spectrometry. Urine samples collected from 55 workers were analysed for hexamethylene diamine (HDA) by gas chromatography coupled with mass spectrometry. Findings are discussed. HDA was detected in urine of 25% of the spray painters. In addition, HDA was detected in urine of a large proportion of non-spray painters in car body repair shops. Although painting with lacquers containing isocyanates results in the highest external exposures to HDI and oligomers, workers that do not perform paint related tasks are significantly exposed.
Descriptors (primary) hexamethylene diisocyanate; coachwork; exposure evaluation; spray coating
Descriptors (secondary) dibutylamine; personal sampling; toluene; inhalation; determination in urine; breathing atmosphere; sampling and analysis; determination in air; skin absorption
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Industries and occupations
Browse category(ies) Surface treatment
Motor vehicle manufacturing industry
Exposure evaluation
Isocyanates
Cyano compounds