|Document ID (ISN)||107798|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Pronk A., Yu F., Vlaanderen J., Tielemans E., Preller L., Bobeldijk I., Deddens J.A., Latza U., Baur X., Heederik D.
||Dermal, inhalation and internal exposure to 1,6-HDI and its oligomers in car body repair shop workers and industrial spray painters
||Sep. 2006, Vol.63, No.9, p.624-631. Illus. 37 ref.
||The objective of this study was to evaluate exposure to hexamethylene diisocyanate (HDI) and its oligomers among car body repair shop workers and industrial spray painters. A total of 95 personal samples were collected from six car body repair shops and five industrial paint shops and analysed using impingers with di-n-butylamine (DBA) in toluene. In parallel, dermal exposure was assessed using nitrile rubber gloves submerged into a solution of DBA in toluene after sampling. Analysis for HDI and its oligomers was performed by liquid chromatography coupled with mass spectrometry. Urine samples collected from 55 workers were analysed for hexamethylene diamine (HDA) by gas chromatography coupled with mass spectrometry. Findings are discussed. HDA was detected in urine of 25% of the spray painters. In addition, HDA was detected in urine of a large proportion of non-spray painters in car body repair shops. Although painting with lacquers containing isocyanates results in the highest external exposures to HDI and oligomers, workers that do not perform paint related tasks are significantly exposed.
||hexamethylene diisocyanate; coachwork; exposure evaluation; spray coating
||dibutylamine; personal sampling; toluene; inhalation; determination in urine; breathing atmosphere; sampling and analysis; determination in air; skin absorption
||D - Periodical articles
|Country / State or Province||Netherlands|
||Metal production and metalworking
|Broad subject area(s)
Industries and occupations
Motor vehicle manufacturing industry