|Document ID (ISN)||107556|
|ISSN - Serial title
||0019-8366 - Industrial Health
|Convention or series no.
||Bianchi C., Bianchi T.
||Malignant mesothelioma: Global incidence and relationship with asbestos
||June 2007, Vol.45, No.3, p.379-387. Illus. 89 ref.
||08-0066.pdf [in English]
||Literature survey. Mesothelioma incidence varies markedly from one country to another. The areas of high incidence generally correspond to the sites of industries with high asbestos use, such as shipbuilding and asbestos-cement industry. However, in some countries with high asbestos consumption, mesothelioma incidence is low. The reasons for this situation are not clear. Mesotheliomas generally develop after long-time exposures to asbestos and with latency periods of often more than 40 years. An inverse relationship exists between intensity of asbestos exposure and the length of the latency period. Some recent studies show that the risk increases with the duration of exposure. Possible co-factors in the pathogenesis of asbestos-related mesothelioma include genetic predisposition, diets poor in fruit and vegetables, some viruses, immune impairment and recurrent pleural inflammation. While a levelling-off in mesothelioma incidence has been registered in some countries, a worsening of the epidemic is predictable in large parts of the world.
||mesothelioma; frequency rates; risk factors; asbestos
||literature survey; asbestos cement; latency; diet; pleural diseases; job-exposure relation; immunity; shipbuilding industry; length of exposure; dose-response relationship; virus diseases
||D - Periodical articles
|Country / State or Province||Italy|
|Broad subject area(s)
Occupational medicine, epidemiology
Bacterial and parasitic diseases
Viral diseases (other than aids)