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CISDOC database

Document ID (ISN)107552
CIS number 08-165
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 2007
Convention or series no.
Author(s) Lensen G., Jungbauer F., Gonšalo M., Coenraads P.J.
Title Airborne irritant contact dermatitis and conjunctivitis after occupational exposure to chlorothalonil in textiles
Bibliographic information Sep. 2007, Vol.57, No.3, p.181-186. 24 ref.
Abstract Chlorothalonil (= 2,4,5,6-tetrachloroisophthalonitrile) is a pesticide that has been on the market for many years. It is used as a fungicide in agriculture, horticulture and floriculture, as a wood preservative, as well as in paint. This article describes an epidemic of airborne irritant contact dermatitis, conjunctivitis and upper airway complaints among seamstresses in a Portuguese trailer tent factory, which was attributed to chlorothalonil. All exposed workers had work-related skin symptoms. After patch testing, it was shown that none of these were of allergic origin. Instead of allergic reactions, a delayed type of irritation was noticed after 72hr to chlorothalonil and to the textile extracts containing high concentrations of chlorothalonil. Although allergic and irritant contact dermatitis from chlorothalonil has been described before, this is the first report of a delayed type of dermatitis, conjunctivitis and upper airway irritation after exposure to chlorothalonil.
Descriptors (primary) tailors, dressmakers and hatters; conjunctivitis; skin diseases; 2,4,5,6-tetrachloroisophthalonitrile
Descriptors (secondary) airborne dust; irritants; Portugal; skin tests; eczema; delayed effects; allergy tests; case study
Document type D - Periodical articles
Country / State or ProvinceNetherlands; Portugal
Subject(s) Textile and clothing industries
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the eye and vision damage
Cyano compounds
Skin diseases