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Document ID (ISN)107543
CIS number 08-152
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2007
Convention or series no.
Author(s) Chang S.J., Chen C.J., Shih T.S., Chou T.C., Sung F.C.
Title Risk for hypertension in workers exposed to carbon disulfide in the viscose rayon industry
Bibliographic information Jan. 2007, Vol.50, No.1, p.22-27. Illus. 24 ref.
Abstract This study assessed the hypertension risk for male rayon workers exposed to carbon disulfide (CS2). A total of 251 exposed workers and 226 unexposed administrative clerks at two rayon plants in Taiwan received health examination and interviews. CS2 levels were measured in air at the worksite. Hypertension was more prevalent among exposed workers (43.4%) than among controls (7.1%) with greater impact on systolic blood pressure than diastolic. Multivariate logistic regression analysis showed a significant dose-response relationship between hypertensive risk and cumulative exposure index, with an odds ratio of 15.1 for workers exposed to 343-468 ppm-years of CS2. The overall risk was 7.6 times higher for rayon workers. The risk increased significantly after more than 10 years of employment, suggesting that it takes a long exposure period to develop hypertension for rayon workers with CS2 exposure.
Descriptors (primary) hypertension; viscose rayon industry; risk factors; Taiwan (China); carbon disulfide; male workers
Descriptors (secondary) latency; exposure evaluation; case-control study; medical examinations; length of exposure; dose-response relationship; statistical evaluation; long-term exposure
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Chemicals, plastics and rubber
Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Cardiovascular diseases
Inorganic sulfur compounds