|Document ID (ISN)||107429|
|ISSN - Serial title
||1545-9624 - Journal of Occupational and Environmental Hygiene
|Convention or series no.
||Fustinoni S., Mercadante R., Campo L., Scibetta L., Valla C., Consonni D., Foà V.
||Comparison between urinary o-cresol and toluene as biomarkers of toluene exposure
||Jan. 2007, Vol.4, No.1, p.1-9. Illus. 31 ref.
||This case-control study compared urinary o-cresol (U-OC) and urinary toluene (U-TOL) as biomarkers of occupational exposure to toluene. One hundred healthy male rotogravure printing workers and 161 male and female control subjects unexposed to toluene were studied. Personal exposure to airborne toluene (TOL-A) during the shift was determined as a time weighted average. Simple analytical procedures based on solid phase micro-extraction followed by gas chromatography-mass spectrometry analysis were applied to the determination of end-shift U-OC and U-TOL. Median TOL-A was 48mg/m3 in printers and 0.021mg/m3 in controls. U-OC was 0.185mg/g creatinine in printers and 0.027mg/g in controls. U-TOL was 7.6µg/L in printers and 0.140µg/L in controls. U-TOL was found to be a slightly more reliable biomarker to toluene exposure than U-OC.
||o-cresol; exposure tests; toluene
||personal sampling; reliability; case-control study; comparative study; sampling and analysis; determination in air; determination in urine; breathing atmosphere
||D - Periodical articles
|Country / State or Province||Italy|
||Toxic and dangerous substances
|Broad subject area(s)